✨📕 The NEWThe NEW Collegiate Dictionary, 12th Edition Over 5,000 words added — Buy Now! Collegiate DictionaryBuy Now!

thick filament

noun

: a myofilament of one of the two types making up myofibrils that is 10 to 12 nanometers (100 to 120 angstroms) in width and is composed of the protein myosin compare thin filament

Browse Nearby Words

Cite this Entry

“Thick filament.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/thick%20filament. Accessed 4 Dec. 2025.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!